Otega Oweh scored 21 points and grabbed 12 rebounds, but No. 9 Kentucky lost at Vanderbilt 74-69 on Saturday.
Ansley Almonor, who started in place of the injured Andrew Carr, scored 12 points and Jaxson Robinson added 11. However, the Cats committed 17 turnovers.
Kentucky (14-5, 3-3 Southeastern Conference) plays at Tennessee Tuesday night at 7:00.